Hyaluronic Acid

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Description

Description:
Hyaluronic acid (HA) is produced by keratinocytes and is a member of a large family of glycosaminoglycans, the main components of the extracellular matrix. It is abundant in tissues and fluids, with the highest concentrations in synovial fluid, vitreous humor and skin. HA helps to support joint health and provides supplemental support for skin health.‡

Science:
FUNCTIONS Hyaluronic acid (HA) is produced by keratinocytes and is a member of a large family of glycosaminoglycans which are the main components of the extracellular matrix. It is abundant in tissues and fluids with the highest concentrations in synovial fluid, vitreous humor and skin. Studies have revealed that most HA properties depend on its molecular size. Many sources of HA consist of a high molecular weight which is too large to be absorbed in the intestines. HyaMax® sodium hyaluronate provides a low molecular weight source of hyaluronic acid produced through a fermentation process. In a pharmacokinetic study, orally administered HyaMax hyaluronic acid was incorporated into joints, connective tissue and skin with a particular affinity for cartilaginous joints.†
Synovial fluid of the joints provides shock absorption and lubrication for movement; as we age this fluid decreases. Supplementation with oral HA has been shown to help retain more synovial fluid and protect the joints, as well as modulate prostaglandin production.† It has also been shown to support the skin by promoting healthy turnover and renewal of keratinocytes moderating the appearance of fine lines and age spots.†

INDICATIONS Hyaluronic Acid may be a useful dietary supplement for individuals wishing to support healthy joint function and skin health.†
FORMULA (#202262) Each vegetarian capsule contains: Hyaluronic acid (low molecular weight)…………………….70 mg
Other ingredients: Cellulose, vegetarian capsule.

HyaMax® is a U.S.A registered trademark of Fenchem
SUGGESTED USE As a dietary supplement, adults take 1 capsule or as directed by your healthcare professional.
SIDE EFFECTS No adverse side effects have been reported.
STORAGE Store in a cool, dry place, away from direct light. Keep out of reach of children.
REFERENCES
Volpi N, Schiller J, Stern R, Soltés L. Curr Med Chem. 2009;16(14):1718-45.
Engström-Laurent A, Hällgren R. Ann Rheum Dis. 1985 Feb;44(2):83-8.

Petrella RJ, DiSilvestro MD, Hildebrand C. Arch Intern Med. 2002 Feb 11;162(3):292-8.
Kawada C, Yoshida T, Yoshida H, et. Al. Ingested hyaluronan moisturizes dry skin. Nutr J. 2014 Jul 11;13:70.

Papakonstantinou E, Roth M, Karakiulakis G. 2012 Jul 1;4(3):253-8.
Gariboldi S, Palazzo M, Zanobbio L, et. al. J Immunol. 2008 Aug 1;181(3):2103-10.
Pauloin T, Dutot M, Joly F, Warnet JM, Rat P. Mol Vis. 2009;15:577-583.
Agren UM, Tammi RH, Tammi MI. Free Radic Biol Med. 1997;23(7):996-1001.
For more information on Hyaluronic Acid® visit douglaslabs.com † These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease

Supplement Facts:
Amount Per Serving
Serving Size 1 Vegetarian Capsule • Servings Per Container 60
each vegetarian capsule contains:
Hyaluronic Acid (from sodium hyaluronate)
70 mg
(low molecular weight)
Other ingredients: Microcrystalline cellulose, hydroxypropyl methylcellulose (capsule)
Suggested Usage: 1 capsule, 1-2 times daily

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